N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Names and Identifiers

Name	N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
Synonyms	AZD9291 1 OSIMERTINIB INTERMEDIATE 1 N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine 2-PyriMidinaMine, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methyl-1H-indol-3-yl)- (4-Fluoro-2-methoxy-5-nitro-phenyl)-[4-(1-methyl-1h-indol-3-yl)-pyrimidin-2-yl]-amine N-(4-fluoro-2-methoxy-5-nitrophenyl)- 4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)
CAS	1421372-94-2
EINECS	806-156-3

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Physico-chemical Properties

Molecular Formula	C20H16FN5O3
Molar Mass	393.37
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	>250°C (dec.)
Boling Point	639.3±65.0 °C(Predicted)
Solubility	DMSO (Slightly, Heated)
Appearance	Form Solid, color Light Yellow to Yellow
Color	Light Yellow to Yellow
pKa	2.02±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Use	Uses This product is used as a reagent to synthesize dihydropyrroloquinoline derivatives with anti-cancer activity and as an EGFR regulator to inhibit L858R/T790M.

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Upstream Downstream Industry

Raw Materials	3-(2-chloropyriMidin-4-yl)-1-Methylindole 4-fluoro-2-Methoxy-5-nitroaniline 1-Methylindole 2,4-DIFLUORO-5-NITROANILINE 3-(2-chloropyriMidin-4-yl)-1H-indole 4-FLUORO-2-METHOXYANILINE Indole 2,4-Difluoroaniline
Downstream Products	AZ 7550

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Nature

Solubility

DMSO (Slightly, Heated)

Last Update：2024-04-10 22:29:15

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)

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Nantong Reform Petro-Chemical CO., LTD.

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Jiangsu Pules Biotechnology Co.,Ltd.

Shanghai Yuanye Bio-Technology Co., Ltd.

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N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)

Raw Materials for N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)

4-fluoro-2-Methoxy-5-nitroaniline
3-(2-chloropyriMidin-4-yl)-1H-indole
Indole
2,4-Difluoroaniline

Downstream Products for N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)

AZ 7550

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

CAS: 1421372-94-2

Molecular Formula: C20H16FN5O3

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Names and Identifiers

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Physico-chemical Properties

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Upstream Downstream Industry

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Nature

Supplier List

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) Request for Quotation

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

CAS: 1421372-94-2

Molecular Formula: C20H16FN5O3

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Names and Identifiers

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Physico-chemical Properties

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Upstream Downstream Industry

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2) - Nature

Supplier List

N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)